BiggestDE
Bro make him ingest posions because his regen will helo him become immune. practice moviing blood inside tth e body for better oxygen consumption and therefore more stamina as muscle work for longer more efficiently. Also maybe you can remove impurities from his blood or something. use blood in his body to act as pressure and try not to use your blood. like everytjme it goes out of body it will evaporate otheriwse orochimaru or someone might get it?