Logical_Dot
There is a bit loophole here, first hokage died because of ashura chakra. He got disease, in sasuke retsuden. Naruto also got the same disease it was because of the abundant of yang chakra being used. He and 2nd hokage are not poisoned by daimyo.
Hmm! Well, I can't do it now as I have already added this idea. Still, what exactly went wrong with Ashura's chakra? Or it was just told that he fell ill because of Asura's chakra?
ZoroTraineeWriter:It was because of ashura chakra. Even hagoroml has the same disease, same like naruto. But in naruto cases, sasuke find cure for him. Meanwhile in Hashirama, they didnt know about asura and indra otsutsuki. So when he got sick, they didnt find cure